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Postion:Product Catalog >Analytical Chemistry>Standard>Pharmaceutical Impurity Reference Standards>Guanidine
Guanidine
  • Guanidine

Guanidine NEW

Price $195 $483 $692
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-06-09

Product Details

Product Name: Guanidine CAS No.: 113-00-8
Purity: 97% Supply Ability: 10g
Release date: 2025/06/09

Product Introduction

Bioactivity

NameGuanidine
DescriptionGuanidine is a strong chaotropic agent and a strong denaturant of proteins.
In vitroGuanidine at low concentrations refolds acid-unfolded apomyoglobin and cytochrome c, stabilizing the molten globule state, i.e. a compact denatured state with a significant amount of secondary structure, but substantially disordered tertiary structure. Guanidine (> 1 M) causes co-operative unfolding of the molten globule state. [1] Guanidine at millimolar concentrations, is able to causes efficient loss of the normally stable [PSI+] element from yeast cells. 5 mM Guanidine in growth media cures [PSI+] and other prions of yeast. 5 mM Guanidine significantly reduces Hsp104-mediated basal and acquired thermotolerance by 30-fold and 50 fold. [2]
In vivoTwo injections of Guanidine at 145 mg/kg per injection is significantly reducing in the death rate of infant mice infected with ten LD50 of coxsackievirus A16 is observed when they are treated 58 h after infection. [3]
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsGuanidine

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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