Guanethidine NEW
| Price | Get Latest Price | |
| Package | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Guanethidine | CAS No.: 55-65-2 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Guanethidine |
| Description | Guanethidine sulphate, synthesized in 1959, is thought to lowing blood pressure by interfering with the metabolism of chemical transmitter substances in post-ganglionic sympathetic nerve fibres. |
| In vitro | Sympathetic fibers ablation is associated with a loss of rat endothelial cell marker (RECA), but no significant effect of guanethidine was found on the survival of endothelial cells and mesenchymal stem cells in vitro [1]. |
| In vivo | Guanethidine (30 mg/kg, s.c., 1 h) administration does not alter IL-18 induced hypernociception in TNFR1 (-/-) mice, indicating that this sympathetic blocker is ineffective in this context [2]. This outcome was observed in a study involving WT Balb/c, TNFR1 (-/-), and IFN-γ (-/-) mice, with guanethidine diluted in saline. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | 1 [2 (azocan 1 yl)ethyl]guanidine | Guanethidine | 1[2(azocan1yl)ethyl]guanidine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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