GSK 690 Hydrochloride NEW
Price | $1450 | $1936 |
Package | 100mg | 200mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: GSK 690 Hydrochloride | CAS No.: 2436760-79-9 |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | GSK 690 Hydrochloride |
Description | GSK 690 (Hydrochloride) is a reversible lysine-specific demethylase 1 (LSD1) inhibitor with a Kd of 9 nM and an IC50 of 37 nM. |
In vitro | GSK690 (1-10 μM) synergizes with JNJ-26481585 to promote cell death across four RMS cell lines (RD, RH30, RMS13, and TE381.T cells), impacting the equilibrium of pro- and antiapoptotic proteins at 1 μM for RD cells and at 10 μM for RH30 cells. This combined treatment triggers caspase-dependent apoptosis at these same concentrations for RD and RH30 cells, respectively, and amplifies JNJ-26481585-induced G2/M phase arrest. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 125 mg/mL (307.94 mM), Sonication is recommended. |
Keywords | GSK 690 Hydrochloride | GSK690 Hydrochloride | GSK-690 Hydrochloride |
Inhibitors Related | LSD1-IN-24 | Tranylcypromine hemisulfate | DDP-38003 dihydrochloride | GSK-LSD1 dihydrochloride | GSK-J4 | FY-21 | Daminozide | Zavondemstat | AS8351 | Procaine hydrochloride | JIB-04 | KDM4-IN-4 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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