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Postion:Product Catalog >GSK-3β inhibitor 1
GSK-3β inhibitor 1
  • GSK-3β inhibitor 1

GSK-3β inhibitor 1 NEW

Price $71 $166 $291
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: GSK-3β inhibitor 1 CAS No.: 187325-53-7
Purity: 99.08% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameGSK-3β inhibitor 1
DescriptionGSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.
In vivoGSK-3β inhibitor 1(compound 3a) inhibits GSK-3β with IC50 4.19 nM. In a cell-based assay 3a shows no significant leucocyte toxicity at 10 M and is moderately cytotoxic against A549 cells. Compound 3a demonstrated high antidiabetic efficacy in obese streptozotocin-treated rats improving glucose tolerance at a dose of 50 mg/kg body weight thus representing an interesting lead for further optimization.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 30 mg/mL (134.99 mM), Sonication is recommended.
KeywordsGSK-3 | inhibit | Glycogen synthase kinase 3 | Glycogen synthase kinase-3 | GSK3β inhibitor 1 | GSK-3β inhibitor 1 | Inhibitor | GSK-3b inhibitor 1 | GSK 3β inhibitor 1 | GSK-3beta inhibitor 1
Inhibitors RelatedPHA-767491 | Cromolyn sodium | GSK 3 Inhibitor IX | CHIR-99021 | AT7519 | 5-Bromoindole | 4-Chloro-2'-bromoacetophenone | SNS-032 | CHIR-99021 HCl | GSK-3 Inhibitor 5 | MeBIO | 1-Azakenpaullone
Related Compound LibrariesAnti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Antidepressant Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Neuroprotective Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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