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Postion:Product Catalog >GS-829845
GS-829845
  • GS-829845

GS-829845 NEW

Price $39 $57 $90
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: GS-829845 CAS No.: 1257705-09-1
Purity: 99.78% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameGS-829845
DescriptionGS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life than the parent.
In vivoFilgotinib did not alter metformin exposures, indicating that filgotinib and GS-829845 do not inhibit OCT2 and MATE1/2K at the clinical doses. Filgotinib was generally well-tolerated when administered alone or with the co-administered drugs in the studies. Results from these studies were the basis to enable the use of P-gp modulators and substrates of OCT2, MATE1, and MATE2K with filgotinib without the need for dose modifications in the current approved rheumatoid arthritis population.[2]
StorageShipping with blue ice.
Solubility InformationDMSO : 90.0 mg/mL (251.8 mM), Sonication is recommended.
KeywordsGS 829845 | GS829845 | GS-829845
Inhibitors RelatedDelgocitinib | Clofibric acid | Mycophenolate Mofetil | CLOZAPINE N-OXIDE | Monomethyl fumarate | Ruxolitinib | Tofacitinib Citrate | Isonicotinic acid | Ruxolitinib phosphate | Ampyrone | 4-Methylamino antipyrine | Nicotinamide N-oxide
Related Compound LibrariesBioactive Compound Library | Kinase Inhibitor Library | Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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