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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>GMB-475
GMB-475
  • GMB-475

GMB-475 NEW

Price Get Latest Price
Package 100mg 500mg 1000mg
Min. Order: 1mg
Supply Ability: 100G
Update Time: 2024-11-19

Product Details

Product Name: GMB-475 CAS No.: 2490599-18-1
Min. Order: 1mg Purity: 98%
Supply Ability: 100G Release date: 2024/11/19

GMB-475 is a BCR-ABL1 tyrosine kinase degrader based on PROTAC, overcoming BCR-ABL1-dependent drug resistance. GMB-475 targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel Lindau (VHL).resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.

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