Glafenine Hydrochloride NEW
| Price | $33 | $48 |
| Package | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Glafenine Hydrochloride | CAS No.: 65513-72-6 |
| Purity: 98.91% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Glafenine Hydrochloride |
| Description | Glafenine Hydrochloride is an anti-inflammatory agent. |
| Cell Research | Glafenine hydrochloride is added to the culture medium of the smooth muscle cells at three concentrations (10 μM, 50 μM, 100 μM). After 4 days of treatment, cells are harvested and the absolute cell number is counted[3]. |
| In vitro | Glafenine enhances the surface expression of mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in baby hamster kidney (BHK) cells, achieving 40% of the expression levels seen in wild-type CFTR[2]. Additionally, Glafenine hydrochloride suppresses the proliferation and clonogenic capabilities of human aortic smooth muscle cells (haSMCs) and endothelial cells (ECs) in a dose-responsive manner, leading to a blockade at the G2/M phase of the cell cycle and a decline in the G1 phase. Moreover, it dose-dependently impairs the migratory capacity of haSMCs and decreases the level of the extracellular matrix protein tenascin[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL |
| Keywords | inhibit | Glafenine | Glafenin | Inhibitor | Glafenine Hydrochloride | Glafenin Hydrochloride |
| Inhibitors Related | Novobiocin Sodium | Prazosin hydrochloride | Thiethylperazine dimaleate | Glipizide | Vismodegib | Vigabatrin | Chlorpropamide | Probucol | DIDS sodium salt | Acridone |
| Related Compound Libraries | Approved Drug Library | NO PAINS Compound Library | Anti-COVID-19 Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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