Product Details
Product Name:
GEMSA |
CAS No.:
77482-44-1 |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | GEMSA |
Description | GEMSA is a potent inhibitor of enkephalin convertase (Ki = 8.8 nM) with analgesic effects[1]. |
In vitro | GEMSA effectively inhibits the activation of TAFI and porcine CBB, along with preventing the extended lysis time observed in recombinant BAP without causing the lysis of APC fibronectin. Additionally, GEMSA demonstrates inhibition of the increased lysis time associated with porcine CPB, TAFI, and recombinant BAP, APC, exhibiting EC50 values of 0.34 μM, 100 μM, 115 μM, and 90 μM, respectively. |
In vivo | GEMSA administered intracerebroventricularly (ICV) at a dose of 0.1μg/mg every 3 days results in a 75% elevation in both hypothalamic luteinizing hormone-releasing hormone and serum luteinizing hormone levels, alongside a 60% reduction in serum prolactin concentrations in rats [3]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | 2 Guanidinoethylmercaptosuccinic Acid | 2Guanidinoethylmercaptosuccinic Acid | GEMSA |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |