Gefitinib NEW
Price | Get Latest Price |
Package | 1g |
Min. Order: | 1g |
Supply Ability: | 1kg |
Update Time: | 2024-11-19 |
Product Details
Product Name: Gefitinib | CAS No.: 184475-35-2 |
Min. Order: 1g | Purity: 98% HPLC |
Supply Ability: 1kg | Release date: 2024/11/19 |
(1) Compete for the Mg-ATP binding site on the catalytic region of EGFR-TK and block its signal transmission;
(2) Inhibit the activation of mitogen-activated protein kinase and promote apoptosis;
(3) Inhibit tumor angiogenesis. Iressa was approved by the Japanese Ministry of Health and Welfare for the treatment of advanced NSCLC on July 5, 2002, and was approved by the FDA as a third-line treatment for NSCLC on May 5, 2003. The recommended dose is 250mg, PO, qd.
It is worth noting that the FDA’s decision was approved when Iressa had just completed Phase II clinical trials and Phase III clinical trials had not yet been completed. In 2003, the Lung Cancer Professional Committee of the Chinese Anti-Cancer Association stated in the guidelines for the treatment of inoperable NSCLC: Iressa is recommended for the treatment of locally advanced or distantly metastatic non-small cell lung cancer patients who have failed platinum-based regimens and Docetaxel chemotherapy. [3]
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