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Postion:Product Catalog >G43
G43
  • G43

G43 NEW

Price $195 $430 $636
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-16

Product Details

Product Name: G43 CAS No.: 690693-02-8
Purity: 99.21% Supply Ability: 10g
Release date: 2024/11/16

Product Introduction

Bioactivity

名稱G43
描述G43 is a potent and selective glucosyltransferase inhibitor that inhibits GtfB and GtfC with Kd values of 3.7 μM and 46.9 nM, respectively.G43 exhibits in vitro and in vivo anti-Streptococcus mutans activity and can be used for caries studies.
體外活性G43 (16 h) inhibits Streptococcus mutans biofilm by 85% at a concentration of 12.5 μM.[1] G43 (25 μM; 24 h) reduces glucan production by glycosyltransferase (Gtfs) and continuously inhibits the activities of GtfB and GtfC, with an inhibition rate of 80% for both enzymes.[1] G43 (25 μM; 24 h) has no significant effect on the expression of gtfs (gtfB, gtfC and gtfD) in UA159 mutans Streptococcus mutans.[1] G43 (50 μM; 24-48 h) reduces biofilm formation by reducing the production of water-insoluble exopolysaccharides in wild-type Streptococcus mutans.[2]
體內(nèi)活性G43 (100 μM; administered topically twice daily for 4 weeks; rat with S. mutans UA159 infected) reduces Streptococcus mutans virulence but did not lose weight over the course of the study. in vivo.[1]
存儲條件Shipping with blue ice.
溶解度DMSO : 45 mg/mL (131.83 mM)
關(guān)鍵字G43
相關(guān)產(chǎn)品Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Doxycycline (hyclate) | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Dimethyl sulfoxide | Crystal Violet
相關(guān)庫經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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