Fz7-21 NEW
| Price | $68 | $179 | $289 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: Fz7-21 | CAS No.: 2247635-23-8 |
| Purity: 99.8% | Supply Ability: 10g |
| Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名稱 | Fz7-21 |
| 描述 | Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM). |
| 存儲(chǔ)條件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 10 mM |
| 關(guān)鍵字 | lipid-binding groove | FZD7 | Wnt | Fz7 21 | Wnt–β-catenin | Fz-7-21 | conformation | FZD7 CRD | intestinal organoids | Inhibitor | Fz721 | inhibit | Fz7-21 |
| 相關(guān)產(chǎn)品 | Urea | PRI-724 | Wnt pathway activator 1 | L-quebrachitol | MSAB | EMT inhibitor-1 | XAV-939 | Nefopam hydrochloride | KY-05009 | Bisdemethoxycurcumin |
| 相關(guān)庫(kù) | 成骨分子庫(kù) | 抗結(jié)直腸癌化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 抗卵巢癌化合物庫(kù) | 多肽分子庫(kù) | NO PAINS 化合物庫(kù) | 已知活性化合物庫(kù) | 細(xì)胞骨架化合物庫(kù) | Wnt/Hedgehog/Notch 通路化合物庫(kù) | 神經(jīng)元分化化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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