Product Details
Product Name:
FPL 62064 |
CAS No.:
103141-09-9 |
Purity:
98.79% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | FPL 62064 |
Description | FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase, respectively). |
Animal Research | Animal Model:Female LACA mice (20-30 g) injected with immune complex. Dosage:5 mg/kg, 10 mg/kg, 20 mg/kg. Administration:Intraperitoneal injection. |
In vivo | FPL 62064 inhibited UV irradiation-induced erythema and PGE2 formation in the guinea pig and also oedema formation and eicosanoid production in the mouse ear produced by arachidonic acid. Co-injected with arachidonic acid in rabbit skin, FPL 62064 inhibited oedema and eicosanoid formation. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 250 mg/mL (942.29 mM), Sonication is recommended.
|
Keywords | Cyclooxygenase | LOX | 5-lipoxygenase | inhibit | Prostaglandin | 5-LOX | FPL62064 | COX | Inhibitor | FPL 62064 | synthetase | Lipoxygenase | anti-inflammatory | COX-2 | FPL-62064 |
Inhibitors Related | Ibuprofen | Acetaminophen | Salicylamide | Diclofenac sodium | Diclofenac Potassium | Paradol | Indomethacin sodium hydrate | Trometamol | Glafenine | Revaprazan hydrochloride |
Related Compound Libraries | Ferroptosis Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | ReFRAME Related Library | Inhibitor Library | Cosmetic Ingredient Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:1135210-68-2
$35.00 / 5mg
-
CAS:40785-97-5
$86.00 / 1mg
-
CAS:95445-79-7
$293.00 / 1mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$1520.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-23 |