FIDAS-3 NEW
| Price | $33 | $73 | $118 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: FIDAS-3 | CAS No.: 1266684-01-8 |
| Purity: 97.75% | Supply Ability: 10g |
| Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名稱 | FIDAS-3 |
| 描述 | FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding. |
| 體外活性 | FIDAS-3 induces the expression of cell cycle inhibitor, p21WAF1/CIP1. FIDAS-3 (10 μM; 36 h) treatment reduces the levels of both S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in LS174T cells.FIDAS-3 (3 μM; 7 days; LS174T cells) treatment significantly inhibits the proliferation of LS174T cells. FIDAS-3 (3-10 μM) treatment inhibits the expression of c-Myc and cyclinD1 in LS174T CRC cells. |
| 體內(nèi)活性 | FIDAS-3 (20 mg/kg;intraperitoneal injection;daily;for one months;C57BL/6J athymic nude mice) treatment significantly inhibits the growth of xenograft tumors. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 90 mg/mL (347.10 mM), Sonication is recommended. |
| 關(guān)鍵字 | Inhibitor | Wnt | CyclinD1 | anti-proliferation | FIDAS3 | FIDAS-3 | c-Myc | MAT2A | FIDAS 3 | β-catenin | S-adenosylmethionine | anti-cancer | SAH | inhibit | SAM |
| 相關(guān)產(chǎn)品 | Urea | PRI-724 | Wnt pathway activator 1 | L-quebrachitol | MSAB | EMT inhibitor-1 | Wogonin | CHIR-99021 | XAV-939 | Nefopam hydrochloride | KY-05009 | Bisdemethoxycurcumin |
| 相關(guān)庫(kù) | 細(xì)胞重編程化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 表觀遺傳庫(kù) | 抑制劑庫(kù) | 神經(jīng)保護(hù)化合物庫(kù) | 已知活性化合物庫(kù) | 細(xì)胞骨架化合物庫(kù) | 抗癌化合物庫(kù) | Wnt/Hedgehog/Notch 通路化合物庫(kù) | 抗癌活性化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $54.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-12 | |
| $10.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co Ltd
|
2024-12-23 | |
| $5.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-04-24 | |
| $33.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-18 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY