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Postion:Product Catalog >Analytical Chemistry>Standard>Titration standard>Ethylenebis(oxyethylenenitrilo)tetraacetic acid
Ethylenebis(oxyethylenenitrilo)tetraacetic acid
  • Ethylenebis(oxyethylenenitrilo)tetraacetic acid

Ethylenebis(oxyethylenenitrilo)tetraacetic acid NEW

Price $8 $6 $2
Package 1kg 100kg 1000kg
Min. Order: 1kg
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-04-24

Product Details

Product Name: Ethylenebis(oxyethylenenitrilo)tetraacetic acid CAS No.: 67-42-5
Min. Order: 1kg Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/04/24
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
Contact person: Jessica

1. Product information


Names

Nameethylene glycol bis(2-aminoethyl)tetraacetic acid
SynonymMore Synonyms

 EGTA Biological Activity

DescriptionEGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA significantly inhibited the substrate adherence capacity of inflammatory macrophages[1][2].
Related Catalog
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
In VitroEGTA, proposed as endodontic irrigant, decreases substrate adherence capacity of inflammatory macrophages in a time- and dose-dependent manner. The EGTA concentration that causes an IC50 is 202 mM. Chelators react with calcium ions in the hydroxyapatite crystals to produce a metallic chelate. Removal of calcium ions from the dentine makes the dentinal tissue softer, especially the hydroxyapatite-rich peritubular dentin and increases the diameter of exposed dentinal tubules[2].
References

[1]. Harris RA, Hanrahan JW. Effects of EGTA on calcium signaling in airway epithelial cells. Am J Physiol. 1994;267(5 Pt 1):C1426-C1434. doi:10.1152/ajpcell.1994.267.5.C1426

[2]. Segura-Egea JJ, Jiménez-Rubio A, Rios-Santos JV, Velasco-Ortega E, Calvo-Gutierrez JR. In vitro inhibitory effect of EGTA on macrophage adhesion: endodontic implications. J Endod. 2003;29(3):211-213.

 Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point678.0±55.0 °C at 760 mmHg
Melting Point241 °C (dec.)(lit.)
Molecular FormulaC14H24N2O10
Molecular Weight380.348
Flash Point363.9±31.5 °C
Exact Mass380.143097
PSA174.14000
LogP-2.53
Vapour Pressure0.0±4.5 mmHg at 25°C
Index of Refraction1.547
Storage conditionStore at RT.
Water Solubilityslightly soluble



2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


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3. Shipping

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4. Contact information

For more details, pls contact us freely.

Mob: 86 17630978909

WhatsApp/Skype/Wechat/LINE: 86 17630978909

Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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