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Postion:Product Catalog >API>Hormones and the Endocrine System>Estrogen and progestin drugs>Estriol
Estriol
  • Estriol
  • Estriol
  • Estriol
  • Estriol
  • Estriol

Estriol NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-07-27

Product Details

Product Name: Estriol CAS No.: 50-27-1
EC-No.: 200-022-2 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/07/27

CAS:50-27-1
MF:C18H24O3
MW:288.38
EINECS:200-022-2
Product Categories:Inhibitors;API;Intermediates & Fine Chemicals;Steroid and Hormone;THEELOL;Hormone Drugs;Steroids;Hormone;Biochemistry;Hydroxysteroids;Metabolites & Impurities;Pharmaceuticals;APIs;50-27-1;Elisa Kit-plant ELISA Kit
Mol File:50-27-1.mol
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Estriol Chemical PropertiesMelting point 280-282 °C(lit.)alpha D25 +58° ±5° (0.04 g in 1 ml dioxane)Boiling point 370.61°C (rough estimate)density 1.27refractive index 58 ° (C=0.4, Dioxane)Fp 9℃storage temp. 2-8°Csolubility Practically insoluble in water, sparingly soluble in ethanol (96 per cent).form neatpkapKa 10.38±0.02(H2O t=23±2 Iunspeci?ed) (Uncertain)color White to Off-WhiteWater Solubility 3.2mg/L(25 oC)Merck 3707BRN 2508172InChIKeyPROQIPRRNZUXQM-ZXXIGWHRSA-NCAS DataBase Reference50-27-1(CAS DataBase Reference)NIST Chemistry ReferenceEstriol(50-27-1)EPA Substance Registry SystemEstriol (50-27-1)
UsesIt belongs to estrogen drug. It can be used for treating leukopenia, various kinds of menopathy, senile vaginitis, and menopausal syndrome. You may also get temporary breast swelling and lumps, menstrual cycle disorders with self-recovery after stopping the drug for about 1 month. Patients of breast hyperplasia, breast lumps, and cancer potentially being related to female hormone-related cancer, aplastic anemia and liver disease patients should be disabled.Production methodTake estrone as raw material; go through acetylation, epoxidation, and reduction to obtain the estriol products.
Estrone [acetylation] → [16, 17-epoxidation] → [rearrangement] → [Restore] → [hydrolysis] → finished product of estriol.
Estrone acetate successively goes through followed enolization, acetylation, epoxidation and reduction to obtain it.DescriptionEstriol is significantly less active than estradiol; however, it has a selective ability to stimulate blood flow and restoration of genital epithelium. In addition, using this drug reduces mental symptoms of menopausal syndrome. It is used in the premenopausal and menopausal periods, for skin atrophy and signs of genital degeneration, and so on.DescriptionEstriol is a metabolite of estradiol and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from <10 ng/ml at 8-10 weeks gestation to approximately 150 ng/ml at week 38. The majority of the estriol synthesized in the later stages of pregnancy originates from fetal dehydroepiandrosterone sulfate (DHEAS) and serves as a direct marker of fetal adrenal gland activity. Saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels. Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.Chemical PropertiesWhite or almost white, crystalline powder.Uses17b-estradiol metabolite, primary estrogen in urineUsesA metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone EstradiolUsesA metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).

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Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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