Product Name: Eptifibatide CAS NO: 188627-80-7

Synonyms:

Eptifibatide acetate salt;

N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;

Chemical & Physical Properties:

Appearance: White to off-white solid

Assay :≥99.00%

Density: 1.605 g/cm3

Refractive Index: 1.735

Storage: Refrigerator

Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.

Integrilin is sold in two strengths, globally: vials containing 2mg/ml (20mg totally) and 0.75mg/ml (75mg totally). A third size is sold in the US: 100 ml vials containing 2mg/ml (200mg totally).