Eprosartan Mesylate NEW
| Price | $40 | $63 | $77 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Eprosartan Mesylate | CAS No.: 144143-96-4 |
| Purity: 99.93% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Eprosartan Mesylate |
| Description | Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker. |
| In vitro | In a study involving brain and spinal cord injured rats, Eprosartan (0.3 mg/kg i.v.) was observed to induce a hypertensive response following spinal cord stimulation. |
| In vivo | Eprosartan effectively inhibits [125I]-Angiotensin II in human tissues (adrenal cortex, liver, cloned AT1 receptors) with an IC50 range of 1.4-3.9 nM and in rat tissues (mesenteric artery, adrenal cortex, glomeruli) with an IC50 range of 1.5-9.2 nM. In isolated perfused proximal tubules of rabbits, Eprosartan (100 nM) completely blocks the isosmotic fluid absorption induced by Angiotensin II. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 4 mg/mL (7.68 mM) DMSO : 104 mg/mL (199.76 mM) |
| Keywords | inhibit | angiotensin-II | nonpeptid | antihypertensive | Angiotensin Receptor | Eprosartan | AT1 | Inhibitor | Eprosartan Mesylate |
| Inhibitors Related | Tranilast | Enalapril Maleate | Azilsartan Methyl Ester | Sacubitril/Valsartan | Azilsartan | Irbesartan | Losartan | Ramipril | Captopril | Valsartan Methyl Ester |
| Related Compound Libraries | Highly Selective Inhibitor Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug-induced Liver Injury (DILI) Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | NO PAINS Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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