EGFR-IN-73 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: EGFR-IN-73 | CAS No.: 2857033-34-0 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | EGFR-IN-73 |
| Description | EGFR-IN-73 (Compound 3f) effectively inhibits the prevalent EGFR mutation, EGFR Del19, with an IC50 value of 119 nM [1]. |
| In vitro | EGFR-IN-73 (Compound 3f), ranging from 0.01 nM to 10 μM over 72 hours, exhibits low activity against wild-type EGFR and potently binds to EGFR mutants including EGFR d746-750 (Del19), EGFR d747-752/P753S, and EGFR L858R, as well as to a lesser extent with EGFR d752-759 and the oncogenic mutants FLT3 D835Y and FLT3 ITD D835V. The compound demonstrates excellent chemical stability, retaining over 95% under acidic conditions after 3 hours and maintaining above 80% stability at neutral pH 7.4. |
| Storage | Shipping with blue ice. |
| Inhibitors Related | Osimertinib | Lidocaine Hydrochloride hydrate | Lapatinib | Afatinib Dimaleate | Erlotinib hydrochloride | Erlotinib | Neratinib | Chalcone | Genistein | Gefitinib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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