EGFR-IN-16 NEW
| Price | $122 | $195 | $370 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: EGFR-IN-16 | CAS No.: 133550-22-8 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | EGFR-IN-16 |
| Description | EGFR-IN-16 (AG473) is an inhibitor of EGFR in human A431 cells. |
| In vivo | Expressed the EGFR-IN-16 lipoprotein from Neisseria meningitides, flagellin FlaB from Vibrio vulnificus and heat shock protein 70 from Mycobacterium tuberculosis (mHsp70) in Escherichia coli as single proteins and fusion proteins with VP2 protein of infectious bursal disease virus (IBDV).Both cellular and humoral adjuvanticities of the three TLR ligands were compared by immunization of mice in two different ways.Among the three co-administered TLR ligands, recombinant EGFR-IN-16 lipoprotein exhibited the highest cellular and humoral adjuvanticities, including promotion of IL-4, IL-12, IFN-γ and IBDV VP2-specific antibody production.Among the three genetically fused TLR ligands, fusion with EGFR-IN-16 D1 domain exhibited the highest cellular and humoral adjuvanticities. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Epidermal growth factor receptor | inhibit | Inhibitor | AG-473 | EGFR-IN-16 | ErbB-1 | EGFR | AG 473 | HER1 | EGFRIN16 | EGFR IN 16 |
| Inhibitors Related | Amlexanox | Nintedanib | Osimertinib | Lapatinib | Ferulic Acid | Erlotinib hydrochloride | Erlotinib | Neratinib | Formononetin | Genistein | Gefitinib | Pazopanib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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