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Postion:Product Catalog >E 0747
E 0747
  • E 0747

E 0747 NEW

Price $293 $436 $722
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: E 0747 CAS No.: 99599-78-7
Purity: 95.01% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱(chēng)E 0747
描述E 0747 (E0747) is a new antiarrhythmic compound that inhibits arrhythmias by inhibiting Na channels in cardiac cells.
體內(nèi)活性Intravenous injection of 3 mg/kg of E-0747 through a femoral vein cannula over a period of seconds using four canine models of ventricular arrhythmia: digitalis, sedation, arrhythmia, and heart failure concluded that E-0747 inhibits arrhythmia by inhibiting Na channels in cardiomyocytes[1];At a frequency of 1 Hz and a concentration higher than 3 X 10(-7) M, E-0747 decreased the maximum rate of rise (Vmax) of the action potential of Purkinje fibers in porcine heart, whereas the resting membrane potential was unchanged, and E-0747 inhibited Vmax in a rate-dependent manner.The inhibition was about 50% at a concentration of 3 X 10(-6) M with a stimulus of 3.3 Hz.[4].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
關(guān)鍵字E 0747
相關(guān)產(chǎn)品Phenytoin sodium | Lidocaine | Valproic Acid | Lidocaine hydrochloride | L-Aspartic aicd sodium | Mebeverine hydrochloride | Amitriptyline hydrochloride | Riluzole | Benzocaine | Nefopam hydrochloride
相關(guān)庫(kù)疼痛相關(guān)化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 已知活性化合物庫(kù) | 離子通道庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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