Dup-721 NEW
| Price | $32 | $46 | $77 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Dup-721 | CAS No.: 104421-21-8 |
| Purity: 98.53% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Dup-721 |
| Description | DuP-721 is a broad-spectrum, orally active antibacterial agent that inhibits a variety of clinically susceptible and resistant bacteria, particularly [M. tuberculosis]. |
| In vitro | DuP-721 (1.5-4 μg/ml) effectively inhibits both conventional antituberculosis drug-susceptible and -resistant Mycobacterium tuberculosis strains without showing cross-resistance to any tested anti-tuberculosis drugs[1]. It is ineffective against M. avium and M. intracellulare up to 250 μg/ml, but inhibits M. gordonoe and M. fortuitum at 3.9 μg/ml, and M. kansasii and M. scrofulaceum at 1.95 μg/ml and 15.6 μg/ml, respectively[1]. |
| In vivo | DuP-721, the first oxazolidinone showed good activity against M. tuberculosis when given orally or parenterally to experimental animals. DuP-721 (oral gavage; 50-160 mg/kg) is protective against M. tuberculosis infection in mice. DuP-721 protects 100% of the infected animals at 50 mg/kg p.o. dose when administered daily for 17 days, and the same effect is observed at 160 mg/kg dose when the drug is administered only on day 11 and 12 post infection[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (354.70 mM), Sonication is recommended. |
| Keywords | Dup-721 | M. tuberculosis | anti-tuberculosis | Mycobacterium tuberculosis | Inhibitor | M. intracellulare | inhibit | M. kansassi | Dup 721 | Dup721 | Antibiotic | Bacterial |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Doxycycline (hyclate) | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Dimethyl sulfoxide | Crystal Violet |
| Related Compound Libraries | Bioactive Compound Library | Anti-Bacterial Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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