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Postion:Product Catalog >DSRM-3716
DSRM-3716
  • DSRM-3716

DSRM-3716 NEW

Price $45 $72 $97
Package 50mg 100mg 200mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: DSRM-3716 CAS No.: 58142-99-7
Purity: 99.74% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameDSRM-3716
DescriptionIsoquinoline, 5-iodo- is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a metastable pool of damaged, but viable, axons.
In vitroTreatment with the isoquinoline DSRM-3716produced dose-dependent inhibition of cADPR increase (IC50 = 2.8 μM) and substantial preservation of NAD+ in these cultures in a manner consistent with engagement and inhibition of SARM1 enzymatic NADase activity inside the cells. DSRM-3716prevented NfL release from severed axons in a dose-dependent manner[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (196.03 mM)
Keywordsneurodegenerative | SARM1 | axon | DSRM3716 | 5-Iodoisoquinoline | inhibit | cADPR | Inhibitor | NADase | DSRM-3716 | DSRM 3716
Inhibitors RelatedDehydroisoandrosterone 3-acetate | Bicalutamide | S-23 | Bavdegalutamide | Enzalutamide | Adrenosterone | Allura Red AC | Sunset Yellow FCF | Ostarine | Flutamide
Related Compound LibrariesNuclear Receptor Compound Library | Bioactive Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Anti-Prostate Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Transcription Factor-Targeted Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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