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Postion:Product Catalog >API>Antineoplastic agents>Hormonal antineoplastic drugs>Droloxifene
Droloxifene
  • Droloxifene

Droloxifene NEW

Price $49 $118 $178
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Droloxifene CAS No.: 82413-20-5
Purity: 99.37% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameDroloxifene
DescriptionDroloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats.
In vitroDroloxifene induces apoptosis in MCF-7 cells(10 nM; 16-18 hours)[1].
In vivoDroloxifene (5-20 mg/kg,P.o.;Daily for 4 weeks can bring THE BMD of DFM up to 10mg/kg and completely prevent OVX from reducing the BMC and BMD of DFM at 20mg /kg/day[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 40 mg/mL (103.22 mM), Sonication is recommended.
KeywordsDroloxifene
Inhibitors RelatedKaempferol | Tamoxifen | Estradiol | Estradiol benzoate | ARV-471 | Cholesterol | Estriol | Chrysin | Ethisterone | Estrone
Related Compound LibrariesNuclear Receptor Compound Library | Bioactive Compound Library | Anti-Ovarian Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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