Product Details
Product Name:
DPH |
CAS No.:
484049-04-9 |
Purity:
99.72% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | DPH |
Description | DPH is a potent, cell-permeable activator of c-Abl, demonstrating significant enzymatic and cellular efficacy in stimulating c-Abl activation. |
In vitro | DPH represents the first cell-permeable, small-molecule tool compound for c-Abl activation. DPH binds to the myristoyl binding site. It also prevents the formation of the bent conformation of the αI helix through steric hindrance. Which is a mode of action distinct from the previously identified allosteric c-Abl inhibitor, GNF-2, that also binds to the myristoyl binding site [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 90 mg/mL (267.6 mM), Sonication is recommended.
|
Keywords | DPH |
Inhibitors Related | Imatinib Mesylate | Bosutinib hydrate | Pivanex | Dasatinib | GNF-5 | Ponatinib | Nilotinib monohydrochloride monohydrate | KW-2449 | Nilotinib | Dasatinib monohydrate | Imatinib | Masitinib |
Related Compound Libraries | Bioactive Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Cancer Metabolism Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$0.00/10mg |
VIP1Y
|
Xian confluore Biological Technology Co., Ltd.
|
2024-03-29 |