DL-Laudanosine NEW
Price | $42 | $59 | $93 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: DL-Laudanosine | CAS No.: 1699-51-0 |
Purity: 99.79% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | DL-Laudanosine |
Description | DL-Laudanosine (Laudanosine) is a recognized metabolite of atracurium and cisatracurium. |
In vivo | laudanosine, a metabolite of atracurium and a central nervous system stimulant, might increase the minimum alveolar concentration (MAC) of halothane.?These estimates were used to determine the rates of infusion that would produce steady state plasma concentrations of laudanosine of approximately 200, 400, and 800 ng .?ml-1.?Subsequent infusion of laudanosine in eight rabbits produced mean (+/- SD) steady state plasma concentrations of laudanosine of 234 +/- 56, 457 +/- 66, and 873 +/- 105 ng .?ml-1.?The control value for MAC of halothane was 1.08 +/- 0.28%.?At the lowest steady state plasma laudanosine concentration, MAC did not significantly differ from control (MAC = 1.15 +/- 0.23%, P less than 0.1).?However, at 457 and 873 ng .?ml-1, laudanosine significantly increased the MAC of halothane by 23% and 30%, respectively.?Infusion with saline in two additional rabbits did not affect MAC. Therefore, at the plasma concentrations of laudanosine found in humans after administration of atracurium, laudanosine increased the MAC of halothane in rabbits[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 11 mg/mL (30.77 mM) |
Keywords | Drug Metabolite | DLLaudanosine | DL Laudanosine | DL-Laudanosine | Inhibitor | inhibit |
Inhibitors Related | Nortriptyline hydrochloride | Clofibric acid | Oseltamivir acid | Mycophenolate Mofetil | CLOZAPINE N-OXIDE | Monomethyl fumarate | 3-Methoxytyramine hydrochloride | Isonicotinic acid | Ampyrone | 4-Methylamino antipyrine | Nicotinamide N-oxide | DP-1 hydrochloride |
Related Compound Libraries | Bioactive Compound Library | Alkaloid Natural Product Library | Selected Plant-Sourced Compound Library | Natural Product Library | CNS-Penetrant Compound Library | NO PAINS Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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