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Postion:Product Catalog >Dihydrorotenone
Dihydrorotenone
  • Dihydrorotenone

Dihydrorotenone NEW

Price $115 $279 $443
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Dihydrorotenone CAS No.: 6659-45-6
Purity: 99.58% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameDihydrorotenone
DescriptionDihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
In vitroDihydrorotenone arrested human plasma cancer cells at the G0/G1 phase of the cell cycle. Dihydrorotenone inhibited cyclin D2 transactivation, thus inhibiting its mRNA expression. In addition, Dihydrorotenone upregulated the cell cycle repressors p21 and p53. Dihydrorotenone also increased the phosphorylation level of p53, suggesting the upregulated transactivation function of p53, which was confirmed by the induction of p21, a substrate of activated p53. Moreover, Dihydrorotenone downregulated AKT and ERK phosphorylation, an incentive of cell cycle progression.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 27.5 mg/mL (69.37 mM)
KeywordsApoptosis | Dihydrorotenone | inhibit | Inhibitor | Mitochondrial Metabolism
Inhibitors RelatedStavudine | 5-Fluorouracil | Imeglimin hydrochloride | Myricetin | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | Metronidazole | Sorafenib | Tributyrin | Salicylic acid | Oleic acid
Related Compound LibrariesAnti-Tumor Natural Product Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Rare Natural Product Library | Antiparasitic Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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