Manufacturer Provide Veterinary Raw Material Diaveridine CAS 5355-16-8 Diaveridine HCl

Introduction

1.Product Name:Diaveridine

2.Synonym:DIAVERIDIN

3.CAS NO: 5355-16-8

4.Purity: 99%min
5.Appearance:Almost White or Yellowish Crystalline Powder

  6.Molecular formula: C13H16N4O2

  7.Molecular weight :260.29

  8.Melting Point :233 °C(lit.)

  9.Storage Temperature :Keep in a cool, dry, dark location in a tightly sealed     container or cylinder.

  10.Packing: Bag, drum

Diaveridine is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent. Treatments with Diaveridine for 90 min have a strong bactericidal effect on S. typhimurium TA1535, and no bacterial growth is observed at 10μg/mL or more. Without metabolic activation, treatment with Diaveridine for 48 h, but not 24 h, causes a dose-dependent, significant increase in the frequency of aberrant metaphases. At 100 μg/mL, 60% of the metaphases contain chromosome aberrations.