diABZI STING agonist-1 (Tautomerism) NEW
| Price | $168 | $265 | $502 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: diABZI STING agonist-1 (Tautomerism) | CAS No.: 2138498-18-5 |
| Purity: 99.72% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | diABZI STING agonist-1 (Tautomerism) |
| 描述 | diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. |
| 體外活性 | diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon gene (STING) receptor agonists, with EC50 of 130 and 186 nM for humans and mice, respectively. diABZI STING agonist-1 (Tautomerism) at a concentration of 1 μM showed high selectivity for more than 350 kinases tested[1]. |
| 體內(nèi)活性 | diABZI STING agonist-1 (Tautomerism)(subcutaneous injection; 2.5 mg/kg) induces STING-dependent activation of type I interferon and proinflammatory cytokines in vivo. diABZI STING agonist-1 (Tautomerism) (intravenous; 3 mg/kg) exhibited systemic exposure with a half-life of 1.4 hours and reached a systemic concentration greater than half the maximum effective concentration of STING in mice (EC50) 200 ng/kg) ml). diABZI STING agonist-1 (Tautomerism) (intravenous; 1.5 mg / kg; 43 days) can significantly inhibit tumor growth and significantly improve survival rate (P <0.001). Eight out of 10 mice are tumor-free[1]. |
| 存儲(chǔ)條件 | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | Shipping with blue ice. |
| 溶解度 | DMSO : 100 mg/ml (117.65 mM), Sonication is recommended. |
| 關(guān)鍵字 | Compound 3 | diABZI STING agonist-1 | diABZI STING agonist | Tautomerism |
| 相關(guān)產(chǎn)品 | H-151 | SR-717 | ChX710 | SN-008 | Vadimezan | Dazostinag disodium | C-176 | Cridanimod | CCCP | diABZI STING agonist-1 trihydrochloride | MSA-2 | C-178 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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