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Postion:Product Catalog >DC-05
DC-05
  • DC-05

DC-05 NEW

Price $132 $196 $297
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: DC-05 CAS No.: 890643-16-0
Purity: 98.95% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameDC-05
DescriptionDC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).
In vitroDC-05 is a non-nucleoside DNMT1 inhibitor with low micromolar IC50 values and significant selectivity toward other AdoMet-dependent protein methyltransferases.?DC-05 (1.25, 2.5, 5, and 10 μM) effectively inhibits the proliferation of HCT116 (human colon cancer) and Capan-1 (human pancreatic adenocarcinoma cells) after treatment for 24, 48, and 72 h. DC-05 displays poor potent activities against DNMT3A, DNMT3B, G9a, SUV39H1, MLL1, SET7/9, and PRMT1 (IC50: >200, >200, >150, >150, >150, >150, 37.1 μM) [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (260.76 mM), Sonication is recommended.
KeywordsInhibitor | DC 05 | DC05 | DNMTs | DNA Methyltransferase | DNA MTases | DC-05 | inhibit
Inhibitors RelatedLevetiracetam | Tazemetostat | Piribedil | XY1 | 5-Azacytidine | GSK126 | EPZ015666 | Procainamide hydrochloride | Zebularine | γ-Oryzanol | MRTX-1719 | 5-Methyl-2'-deoxycytidine
Related Compound LibrariesReprogramming Compound Library | Histone Modification Compound Library | Methylation Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Chromatin Modification Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
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