Dapoxetine HCI
| Price | $1 | $72 |
| Package | 10g | 1000g |
| Min. Order: | 1g |
| Supply Ability: | 1000kg |
| Update Time: | 2024-10-23 |
Product Details
| Product Name: Dapoxetine HCI | CAS No.: 129938-20-1 |
| Min. Order: 1g | Purity: 99.99% |
| Supply Ability: 1000kg | Release date: 2024/10/23 |
| Dapoxetine hydrochloride Usage And Synthesis |
| Description | PE is the most common form of male sexual dysfunction affecting 20-40% of men globally at some point in their lives. Ejaculation is a reflex comprising different sensory pathways, motor centers, and nerve pathways. This ejaculatory reflex has been shown to be controlled primarily by serotonin and dopamine. Dapoxetine is a short-acting SSRI. It is differentiated from the existing SSRI treatments for PE by the fact that it can be administered on an as-needed basis. In healthy subjects, dapoxetine is rapidly absorbed after oral administration with a peak plasma concentration (Tmax) occurring between 1.4 and 2 h. Dapoxetine also showed statistically significant improvements in perceived control over ejaculation, PE-related personal distress, and other patient-reported outcomes in all five trials. Dapoxetine treatment was generally well tolerated, with low incidences of discontinuation syndrome, sexual dysfunction, and treatment-emergent mood symptoms. The most common adverse events with dapoxetine included nausea, diarrhea, headache, dizziness, and somnolence. |
| Chemical Properties | Off-white Cryst |
| Originator | Lilly (US) |
| Uses | Selective serotonin reuptake inhibitor (SSRI) |
| Uses | Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. D |
| Uses | A selective serotonin reuptake inhibitor |
| Brand name | Priligy |
| Chemical Synthesis | Dapoxetine can be synthesized in four chemical steps starting from R-1phenyl- 1,3-propanediol via selective tosylation of the primary hydroxy group with p-toluenesulfonyl chloride, triethylamine and 4-(dimethylamino) pyridine (DMAP), and subsequent condensation with 1naphthol by means of sodium- or lithium hydroxide to yield R-3-(1naphthyloxy)- 1-phenylpropanol as the key intermediate. Conversion of the alcohol group to the corresponding mesylate with methanesulfonyl chloride, triethylamine, and DMAP, followed by treatment with dimethylamine affords dapoxetine, which is then acidified to its hydrochloride salt. |
Advantage:
1. Our company is a professional production leading factory in China in pharmaceutical area of many years. Delivery areas of our products:US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.
Payment method: T/T, Western union, Moneygram.
2. Discreet package.The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration.
3. Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.
4. Security Shipping: Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you.
5. We have stock, so we can delivery quickly at the very day when receive the payment.
6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
7. A discount would be given when you make a large order.
Hot Selling Products
| NO. | Product Name | CAS |
| 1 | YK-11 | CAS:431579-34-9 |
| 2 | Rad140 | CAS:1182367-47-0 |
| 3 | AICAR | CAS:2627-69-2 |
| 4 | MK-677 | CAS:841205-47-8 |
| 5 | MK-2866 | CAS:841205-47-8 |
| 6 | LGD-4033 | CAS:1165910-22-4 |
| 7 | SR9009 | CAS:1379686-30-2 |
| 8 | Carphedon | CAS:77472-70-9 |
| 9 | Sunifiram | CAS:314728-85-3 |
| 10 | GW501516 | CAS:841205-47-8 |
| 11 | Andarine S-4 | CAS:401900-40-1 |
| 12 | Dianabol | CAS:72-63-9 |
| 13 | Oxandrolone | CAS:53-39-4 |
| 14 | Oxymetholone | CAS:434-07-1 |
| 15 | Stanozolol | CAS:10418-03-8 |
| 16 | Anastrozole | CAS:120511-73-1 |
| 17 | Exemestane | CAS:107868-30-4 |
| 18 | Clomifene Citrate | CAS:50-41-9 |
| 19 | Tamoxifen Citrate | CAS:54965-24-1 |
| 20 | Toremifene Citrate | CAS:89778-27-8 |
| 21 | Raloxifene | CAS:84449-90-1 |
| 22 | Letrozole | CAS:112809-51-5 |
| 23 | Fluoxymesterone | CAS:76-43-7 |
| 24 | Testosterone Acetate | CAS:1045-69-8 |
| 25 | Testosterone Cypionate | CAS: 58-20-8 |
| 26 | Testosterone Decanoate | CAS: 5721-91-5 |
| 27 | Testosterone Enanthate | CAS:315-37-7 |
| 28 | Testosterone Propionate | CAS: 57-85-2 |
| 29 | Testosterone Phenylpropionate | CAS: 1255-49-8 |
| 30 | Testosterone Isocaproate | CAS: 15262-86-9 |
| 31 | Testosterone Undecanoate | CAS: 5949-44-0 |
| 32 | Sustanon 250 | N/A |
| 33 | Turinabol | CAS: 855-19-6 |
| 34 | Oral Turinabol | CAS: 2446-23-3 |
| 35 | Stanolone | CAS: 521-18-6 |
| 36 | Nandrolone | CAS:434-22-0 |
| 37 | Nandrolone Cypionate | CAS: 601-63-8 |
| 38 | Nandrolone Decanoate (DECA) | CAS: 360-70-3 |
| 39 | Nandrolone Phenypropionate (NPP) | CAS: 62-90-8 |
| 40 | Nandrolone laurate | CAS:26490-31-3 |
| 41 | Nandrolone propionate | CAS:7207-92-3 |
| 42 | Nandrolone Phenylpropionate | CAS:62-90-8 |
| 43 | Nandrolone Undecanoate | CAS:862-89-5 |
| 44 | Boldenone | CAS:846-48-0 |
| 45 | Boldenone Acetate | CAS :2363-59-9 |
| 46 | Boldenone Cypionate | CAS:106505-90-2 |
| 47 | Boldenone Undecylenate | CAS: 13103-34-9 |
| 49 | Drostanolone Propionate (Masteron) | CAS: 521-12-0 |
| 50 | Drostanolone Enanthate | CAS: 472-61-1 |
| 51 | Methenolone Acetate (Primobolan) | CAS: 434-05-9 |
| 52 | Methenolone Enanthate | CAS: 303-42-4 |
| 53 | Trenbolone Series | |
| 54 | Trenbolone | CAS:10161-33-8 |
| 55 | Trenbolone Acetate | CAS: 10161-34-9 |
| 56 | Trenbolone Enanthate | N/A |
| 57 | Trenbolone Hexahydrobenzyl Carbonate | CAS: 23454-33-3 |
| 58 | Epiandrosterone | CAS:481-29-8 |
Company Profile Introduction
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $50.00/1KG |
VIP4Y
|
Hebei Lingding Biotechnology Co., Ltd.
|
2024-12-18 | |
| $0.00/10g |
VIP3Y
|
HangZhou RunYan Pharma Technology Co.,LTD.
|
2024-11-23 | |
| $30.00/10mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
| $0.00/25kg |
VIP1Y
|
Hebei Mojin Biotechnology Co.,Ltd
|
2024-09-10 | |
| $19.00/1KG |
VIP4Y
|
Hebei Chuanghai Biotechnology Co,.LTD
|
2024-08-08 | |
| $0.00/10mg |
VIP1Y
|
ShenZhen H&D Pharmaceutical Technology Co., LTD
|
2024-05-21 | |
| $0.00/25kg |
VIP1Y
|
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
|
2024-05-15 | |
| $23.00/1box |
VIP1Y
|
Shanghai Getian Industrial Co., LTD
|
2024-04-26 | |
| $35.00/1kg |
VIP1Y
|
Sigma Audley
|
2024-03-15 | |
| $10.00/1kg |
VIP1Y
|
Wuhan Xinhao Biotechnology Co., Ltd
|
2024-01-17 |
China- Since: 2023-03-16
- Address: Room 21, Floor 7, Building 3, SBI Chuangye Street, Dongxin Road, Donghu New Technology Development Z
INQUIRY