Dapivirine NEW
| Price | $44 | $81 | $119 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Dapivirine | CAS No.: 244767-67-7 |
| Purity: 99.77% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Dapivirine |
| Description | Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. |
| In vivo | Dapivirine-containing gel at vaginal level inhibits cell-associated HIV infection in mice. [3] More placebo (7 of 12) than Dapivirine (3 of 24) gel users has positive vaginal swab results, with white blood cells being the most common finding. Dapivirine (0.05%) results in Cmax of 715 pg/mL, AUC of 15 ng×h/mL and T1/2 of 89.87 hours in plasma after 14 days post-dose. Mean Dapivirine (0.05%) concentrations in vaginal fluids collected at the introitus, mid vagina, and cervix are in the range of 62-265 μg/g on day 1. [4] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 32 mg/mL (97.1 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Autophagy | Apoptosis | TMC-120 | Dapivirine | Inhibitor | R-147681 | inhibit | TMC 120 | HIV | Reverse Transcriptase | Human immunodeficiency virus | R 147681 |
| Inhibitors Related | Emtricitabine | Hydroxychloroquine | Tributyrin |
| Related Compound Libraries | Bioactive Compound Library | Anti-Viral Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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|---|---|---|---|---|
| $1520.00/25mg |
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2024-10-28 | |
| $1.00/1KG |
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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