Dantrolene sodium hemiheptahydrate NEW
| Price | $30 | $88 |
| Package | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-20 |
Product Details
| Product Name: Dantrolene sodium hemiheptahydrate | CAS No.: 24868-20-0 |
| Purity: 99.72% | Supply Ability: 10g |
| Release date: 2025/05/20 |
Product Introduction
Bioactivity
| Name | Dantrolene sodium hemiheptahydrate |
| Description | Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction. Dantrolene sodium hemiheptahydrate (Sodium dantrolene) is the sodium salt form of dantrolene, a hydantoin derivative, and direct-acting skeletal muscle relaxant. |
| In vitro | Dantrolene sodium can inhibit intracellular Ca2+ release from the sarcoplasmic reticulum. In the linoleic acid emulsion system, Dantrolene sodium has strong antioxidant activity. |
| In vivo | In contrast of the slow soleus (SOL) muscle, Dantrolene sodium (5 mg/kg) has a greater inhibitory on the twitch contraction of the fast extensor digitorum longus (EDL) muscle. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 16.67 mg/mL (41.75 mM), Sonication is recommended. |
| Keywords | Inhibitor | inhibit | Dantrolene sodium Hydrate | Dantrolene sodium hemiheptahydrate | Dantrolene sodium | CalciumChannel | Calcium Channel | Ca2+ channels | Ca channels | Autophagy |
| Inhibitors Related | Stavudine | Sodium 4-phenylbutyrate | L-Ascorbic acid | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Valproic Acid | Curcumin | Paeonol | Naringin | L-Ascorbic acid sodium salt | Gefitinib |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Neuroprotective Compound Library | Inhibitor Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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