Danshensu sodium salt NEW
| Price | $45 | $60 | $85 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Danshensu sodium salt | CAS No.: 67920-52-9 |
| Purity: 99.52% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Danshensu sodium salt |
| Description | Danshensu sodium salt (Sodium Danshensu) is sodium salt of danshensu from the widely used Chinese herb Danshen. It can inhibited phenylephrine- and CaCl2-induced vasoconstriction in Ca2+-free medium. |
| In vitro | The compound Sodium Danshensu was administered in two different methods to assess its toxicity. When orally administered to mice, the LD50 was determined to be 2356.33 mg/kg; conversely, when injected intravenously into rats, the LD50 was found to exceed 1500 mg/kg. |
| In vivo | Danshensu is an effective free radical scavenger and antioxidant. Sodium danshensu exerts a biphasic action on vascular tension, where a low dose may induce minor contractions through a momentary increase in Ca2+ influx, while higher doses predominantly cause significant vasodilation by facilitating the opening of non-selective K+ channels and small-conductance Ca2+-sensitive K+ channels in vascular smooth muscle cells. Additionally, sodium danshensu inhibits vasoconstriction induced by norepinephrine and CaCl2 in a free Ca(2+) medium. Pre-treatment with sodium danshensu can suppress vasoconstriction triggered by norepinephrine and KCl in a dose-dependent manner. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 2 mg/mL (9.08 mM) DMSO : 50 mg/mL (227.11 mM), Heating is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Autophagy | Danshensu sodium salt | DanShenSu sodium sal | Danshensu | inhibit | Inhibitor | Danshensu sodium |
| Inhibitors Related | Stavudine | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Paeonol | Naringin | Gefitinib |
| Related Compound Libraries | Polyphenolic Natural Product Library | Target-Focused Phenotypic Screening Library | Bioactive Compound Library | Chinese Pharmacopoeia Natural Product Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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