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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>Dabrafenib Mesylate
Dabrafenib Mesylate
  • Dabrafenib Mesylate

Dabrafenib Mesylate NEW

Price $40 $57 $72
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Dabrafenib Mesylate CAS No.: 1195768-06-9
Purity: 99.62% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameDabrafenib Mesylate
DescriptionDabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).
In vitroIn human endothelial cells, Dabrafenib inhibits the release of HMGB1 and down-regulates the HMGB1-dependent inflammatory response by enhancing the expression of cell adhesion molecules (CAM)[1]
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 45 mg/mL (73.09 mM)
KeywordsDabrafenib | Raf kinases | Inhibitor | GSK2118436 | Raf | inhibit | GSK 2118436 Mesylate | GSK 2118436 | GSK-2118436 | GSK-2118436 Mesylate | Dabrafenib Mesylate
Inhibitors RelatedRegorafenib monohydrate | Doramapimod | Vemurafenib | Sorafenib | Regorafenib | Dabrafenib | Sorafenib tosylate | PLX-4720 | LY3009120 | GW 441756
Related Compound LibrariesHighly Selective Inhibitor Library | Pain-Related Compound Library | Bioactive Compound Library | Tyrosine Kinase Inhibitor Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | FDA-Approved Kinase Inhibitor Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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