(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate NEW
Price | $111 | $190 | $273 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate | Purity: 96.84% |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate |
Description | (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane. |
In vitro | In opossum kidney (OK) cells, (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate (0.05-10 μM) inhibits PTHrP or PTH-stimulated cAMP formation in causes a concentration-dependent manner. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate (0.1-10 μM) attenuates the inhibition of NapiT promoted by 1 nM of either PTHrP or PTH[1]. |
In vivo | In hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung, administration of (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels[2]. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 50 mg/ml |
Keywords | (D Trp12,Tyr34) pTH (7 34) amide (bovine) acetate | (D-Trp12,Tyr34)-pTH | (D-Trp-12,Tyr34)-pTH (7-34) amide (bovine) acetate | (DTrp12,Tyr34)pTH (734) amide (bovine) acetate | (D-Trp12,Tyr34)-pTH amide Acetate |
Inhibitors Related | Propylthiouracil | Liothyronine | L-Thyroxine | L-Thyroxine sodium | 2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE | Resmetirom | Carbimazole | Liothyronine sodium | 2-Thiouracil | Tiratricol |
Related Compound Libraries | Peptide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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