(D-Ala2)-Leu-Enkephalin NEW
| Price | Get Latest Price | ||
| Package | 1kg | 5kg | 25kg |
| Min. Order: | 0.10000000149011612kg |
| Supply Ability: | 2000kgs |
| Update Time: | 2025-05-04 |
Product Details
| Product Name: (D-Ala2)-Leu-Enkephalin | CAS No.: 64963-01-5 |
| EC-No.: 265-291-0 | Min. Order: 0.10000000149011612kg |
| Purity: 99% | Supply Ability: 2000kgs |
| Release date: 2025/05/04 |
| Product Name: | (D-Ala2)-Leu-Enkephalin |
| Synonyms: | H-TYR-D-ALA-GLY-PHE-LEU-OH;(D-ALA2)-LEU-ENKEPHALIN;D-ALA2-LEU5-ENKEPHALIN;[D-ALA2]-LEUCINE ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-L-leucine;(D-alanine2)leucine enkephalin;L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH |
| CAS: | 64963-01-5 |
| MF: | C29H39N5O7 |
| MW: | 569.65 |
| EINECS: | 265-291-0 |
| Melting point | 160-163.5 °C |
| Boiling point | 991.9±65.0 °C(Predicted) |
| density | 1.257±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF (Slightly), DMSO (Slightly) |
| pka | 3.40±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChIKey | ZHUJMSMQIPIPTF-JMBSJVKXSA-N |
| SMILES | C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N |
| Definition | The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin. |
| benefits | (D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions. |
| References | [1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644. |
Chongqing Zhihe Bio-pharmaceutical Co.,Ltd is mainly focus on cosmetics raw materials, our most competitive products are Phytosphingosine and has varity kinds of Ceramides, we are the the Chinese manufacturer of these.
Other two manufacturers are EVONK Germany and DOOSAN Korea, Chongqing Zhihe has the same quality with them and more competitive price.
With mature fermentation process, Zhihe can provide
ceramide NP1(IIIB),
ceramide NP2,
ceramide III,
ceramide AP(VI),
ceramide EOP,
other water souluble or oil soulble mixture of ceramides, ceramides lipidosome.
Chongqing Zhihe has R&D fermination team and Cosmetic formulation engineers team that can solve the application issues of customers.
Company Profile Introduction
Chongqing Zhihe Bio-pharmaceutical Co., Ltd. was established in August 2015, located at the foot of Jinyun Mountain, National University Science and Technology Park, Beibei District ,Chongqing, mainly engaged in the development and production of Synthetic biology technique chemical raw materials, R&D for fine chemicals technical services, Functional raw material of cosmetics, and products based on microbial fermentation biosynthesis technology (including enzyme preparations), and it is one of the major technology enterprises which are supported by Chongqing Government.
The company has established long-term and stable cooperative relationships with well-known scientific research institutions and universities at domestic and abroad, our company united academic exchanges and technical cooperation continuously, and we jointly conducted scientific research on key technologies, enhanced the company's scientific research strength, and provided a strong guarantee for the sustainable development of the company. At the same time, the company continues to invest huge amount of money in chemical raw materials, preparations, fine chemicals for technological research and development and industrial transformation. At present, the company has reserved Fusidic acid, Luriconazole, duloxetine, hyaluronic acid, L-fucose, phytosphingol, Valencia citroene and naringone and other projects with independent intellectual property rights and huge commercial value, and is carrying out industrialization and market development.
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