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Postion:Product Catalog >CZC-54252 hydrochloride
CZC-54252 hydrochloride
  • CZC-54252 hydrochloride

CZC-54252 hydrochloride NEW

Price $44 $69 $137
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: CZC-54252 hydrochloride CAS No.: 1784253-05-9
Purity: 98.21% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱CZC-54252 hydrochloride
描述CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM.
體外活性CZC-54252 hydrochloride(1.6 nM) fully reverses G2019S LRRK2-induced human neuronal injury to wild-type levels. CZC-54252 hydrochloride inhibits the recombinant human wild-type LRRK2 with an IC50 ranging from 1 to 5 nM. CZC-54252 hydrochloride inhibits the G2019S mutant with an IC50 ranging from 2 to 7 nM in a TF-FRET assay[2].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 30 mg/mL (55.41 mM), Sonication and heating to 60℃ are recommended.
關(guān)鍵字CZC 54252 | CZC54252 hydrochloride | injury | inhibit | LRRK2 | CZC54252 | CZC-54252 | neuronal | Leucine-rich repeat kinase 2 | neuroprotective | CZC-54252 Hydrochloride | Inhibitor | CZC 54252 hydrochloride | CZC 54252 Hydrochloride | LRRK2-G2019S | CZC54252 Hydrochloride
相關(guān)產(chǎn)品PFE-360 | GNE0877 | CZC-25146 | GSK2578215A | GNE-9605 | GNE-7915 | EB-42486 | LRRK2 inhibitor 1 | LRRK2-IN-7 | LRRK2-IN-1 | CCG-1423 | PF-06454589
相關(guān)庫經(jīng)典已知活性庫 | 激酶抑制劑庫 | 抑制劑庫 | 神經(jīng)保護(hù)化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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