Cyproheptadine NEW
| Price | $1130 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: Cyproheptadine | CAS No.: 129-03-3 |
| Supply Ability: 10g | Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | Cyproheptadine |
| Description | Cyproheptadine is a potent, orally active antagonist of the 5-HT 2A receptor with antidepressant, antiserotonergic, antiplatelet, and thromboprotective effects, useful in thromboembolic disorders research [1] [2]. |
| In vitro | Cyproheptadine, in concentrations ranging from 0.01 to 100 nM and applied for 1 minute, effectively inhibits serotonin-enhanced ADP-induced platelet aggregation in mice in a dose-dependent manner in vitro [2]. At a concentration of 10 nM, it also inhibits serotonin-enhanced ADP-induced tyrosine phosphorylation in platelets at 1 μM ADP and 15 μM serotonin levels in vitro [2]. Furthermore, Cyproheptadine suppresses PS exposure (Annexin V), P-selectin, and GPIIb-IIIa (PAC-1 binding) activation in human platelets in vitro [2]. |
| In vivo | Cyproheptadine (1 mg/kg; i.p.; daily, for 5 days; C57BL/6 mice) exerts thromboprotective properties in vivo [2]. Animal Model: C57BL/6 mice (8-10 weeks old) [2] Dosage: 1 mg/kg Administration: Intraperitoneal injection; daily, for 5 days Result: Prolonged occlusion times and tail bleeding times in mice. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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