CXCL-CXCR1/2-IN-1 NEW
Price | $40 | $64 | $129 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-17 |
Product Details
Product Name: CXCL-CXCR1/2-IN-1 | CAS No.: 2415653-55-1 |
Purity: 99.40% | Supply Ability: 10g |
Release date: 2024/11/17 |
Product Introduction
Bioactivity
名稱 | CXCL-CXCR1/2-IN-1 |
描述 | CXCL-CXCR1/2-IN-1 is an orally active and potent inhibitor of the ELR+CXCL-CXCR1/2 pathway with anticancer and anti-angiogenic activity and can be used to study cardiovascular disease and cancer. |
體外活性 | CXCL-CXCR1/2-IN-1 (compound 10; 1-2.5 μM; 24-48h; A498 cells) showed reduced ERK and AKT phosphorylation in A498 cells. CXCL-CXCR1/2-IN-1 also can inhibit the secretion of CXCL1, CXCL5, and CXCL8, which are representative pro-angiogenic ELR+CXCL cytokines.[1] |
體內(nèi)活性 | CXCL-CXCR1/2-IN-1 (1 μM; 48h; Female NOD SCID mice injected with 786 RCC cells) reduces the metastatic area in zebrafish embryos injected with A498 cells.[1] CXCL-CXCR1/2-IN-1 (100 mg/kg; oral gavage; twice a day; for 28 days) inhibits tumor growth in mice.[1] |
存儲條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 2 mg/mL (5.22 mM), Sonication is recommended. |
關(guān)鍵字 | CXCLCXCR1/2IN1 |
相關(guān)產(chǎn)品 | AZD8309 | rac-NBI-74330 | Delmetacin | Tannic acid | Artemotil | CXCR2-IN-1 | LIT927 | Plerixafor octahydrochloride | Nicotinamide N-oxide | Plerixafor |
相關(guān)庫 | GPCR靶點分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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