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Postion:Product Catalog >CRT0273750
CRT0273750
  • CRT0273750

CRT0273750 NEW

Price $48 $118 $193
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: CRT0273750 CAS No.: 1979939-16-6
Purity: 99.49% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCRT0273750
DescriptionCRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM.
In vitroCRT0273750 is also shown to inhibit the migration of 4T1 cells with an EC50 of 0.025μM[1]. CRT0273750 shows high potency in both the biochemical (IC50 = 0.01 μM) and plasma choline release assay(IC50 = 0.014 μM)[1].
In vivoCRT0273750 treatment shows the Cmax, AUC and t1/2 values of 3.8 μM, 3.2 μM.h and 1.4 h, respectively and shows a proportional increase[1].CRT0273750 has a moderate blood clearance, with value of 41 mL/min/kg[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 200 mg/mL (397.68 mM)
Keywordsblood | ATX/LPA | 4T1 | CRT0273750 | Inhibitor | inhibit | clearance | LPA
Inhibitors RelatedTheophylline monohydrate | Diphylline | Acefylline | Roflumilast | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Vardenafil hydrochloride | Doxofylline
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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