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Postion:Product Catalog >CNS-5161 hydrochloride
CNS-5161 hydrochloride
  • CNS-5161 hydrochloride

CNS-5161 hydrochloride NEW

Price $509 $1000 $1360
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: CNS-5161 hydrochloride CAS No.: 160756-38-7
Purity: 99.53% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCNS-5161 hydrochloride
DescriptionCNS-5161 hydrochloride (CNS 5161A) is a new antagonist of NMDA ion-channel. It interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.
In vitroCNS-5161 has potent inhibitory activity in vitro at the NMDA ion channel and is able to displace [3H] MK-801 binding with a Ki of 1.8 nM in synaptosomal membrane preparations from rat brain.
In vivoIn the neonatal rat NMDA excitotoxicity model in vivo, CNS-5161 (i.p.) protects against the necrotic effects of exogenous N-methyl-D-aspartate (ED80: 4 mg/kg). CNS-5161 also demonstrates a 91% inhibition of audiogenic seizures in DBA/2 mice at 4 mg/kg i.p. and exhibits neuroprotective effects following hypoxic/ischaemic brain injury in neonatal rats[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 55 mg/mL (141.61 mM)
KeywordsCNS-5161 Hydrochloride | CNS 5161 Hydrochloride | CNS5161 Hydrochloride
Inhibitors Related(-)-Aspartic acid | Mephenesin | Quinolinic acid | Urethane | Halothane | Riluzole | Ifenprodil Tartrate | Bupivacaine hydrochloride monohydrate | O-Phospho-L-serine | Procaine hydrochloride | Memantine hydrochloride | UBP551
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Antidepressant Compound Library | Neuronal Signaling Compound Library | Neurotransmitter Receptor Compound Library | Neuroprotective Compound Library | Inhibitor Library | PPI Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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