Clofilium tosylate NEW
Price | $48 | $80 | $169 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Clofilium tosylate | CAS No.: 92953-10-1 |
Purity: 99.68% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Clofilium tosylate |
Description | Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells. |
In vitro | Treatment with 0-20 μM Clofilium inhibits viability and proliferation in a time- and concentration-dependent manner in HL-60 cells. Cell viability is significantly reduced in HL-60 cells treated with 2.5 μM to 10 μM Clofilium After 12 hours. Treatment with 10 μM Clofilium induces the proteolytic cleavage of inactive procaspase-3, p34 into its active form, p17 and subsequent cleavage of its substrate PARP.. However, the expression of Bcl-2 and Bax proteins does not change significantly[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 100 mg/mL (196.01 mM), Sonication is recommended. |
Keywords | Clofilium tosylate | Potassium Channel | Clofilium | inhibit | Apoptosis | Inhibitor | KcsA | Clofilium Tosylate |
Inhibitors Related | Minoxidil sulfate | Halothane | Cloperastine hydrochloride | 2,2,2-Trichloroethanol | Indapamide |
Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Hematonosis Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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