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Postion:Product Catalog >Clofilium tosylate
Clofilium tosylate
  • Clofilium tosylate

Clofilium tosylate NEW

Price $48 $80 $169
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Clofilium tosylate CAS No.: 92953-10-1
Purity: 99.68% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameClofilium tosylate
DescriptionClofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.
In vitroTreatment with 0-20 μM Clofilium inhibits viability and proliferation in a time- and concentration-dependent manner in HL-60 cells. Cell viability is significantly reduced in HL-60 cells treated with 2.5 μM to 10 μM Clofilium After 12 hours. Treatment with 10 μM Clofilium induces the proteolytic cleavage of inactive procaspase-3, p34 into its active form, p17 and subsequent cleavage of its substrate PARP.. However, the expression of Bcl-2 and Bax proteins does not change significantly[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (196.01 mM), Sonication is recommended.
KeywordsClofilium tosylate | Potassium Channel | Clofilium | inhibit | Apoptosis | Inhibitor | KcsA | Clofilium Tosylate
Inhibitors RelatedMinoxidil sulfate | Halothane | Cloperastine hydrochloride | 2,2,2-Trichloroethanol | Indapamide
Related Compound LibrariesBioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Hematonosis Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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