Cinanserin hydrochloride NEW
| Price | $30 | $68 | $109 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Cinanserin hydrochloride | CAS No.: 54-84-2 |
| Purity: 99.32% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Cinanserin hydrochloride |
| Description | Cinanserin hydrochloride (SQ 10643), a high-affinity antagonist of the 5-HT2 receptor (Ki: 41 nM), is also a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. |
| In vitro | Cinanserin and Cinanserin hydrochloride inhibit the catalytic activity of SARS-CoV 3CLpro and HCoV-229E 3CLpro (IC50: 4.68 μM and 5.68 μM). Cinanserin/Cinanserin hydrochloride has a binding affinity to SARS-CoV 3CLpro, HCoV-229E 3CLpro, with the KD values of 49.4 μM/78.0 μM for SARS-associated coronavirus (SARS-CoV) 3CLpro[1]. |
| In vivo | Cinanserin (5 mg/kg; intravenous injection; 2 hours; male Wistar rats) treatment significantly reduces systemic burn edema to shamburn levels[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 125 mg/mL (331.62 mM), Sonication is recommended. H2O : 100 mg/mL (265.29 mM）, Sonication is recommended. |
| Keywords | edema | replication | Serotonin Receptor | Cinanserin hydrochloride | leukocyte | virus | burn | 3C-like | Cinanserin Hydrochloride | proteinase | endothelial | Influenza Virus | Cinanserin | SQ-10643 | Inhibitor | 5-hydroxytryptamine Receptor | systemic | 5-HT Receptor | inhibit | 5-HT2 | SQ10643 |
| Inhibitors Related | Rifampicin | Alverine citrate | Acetylcysteine | Dapoxetine hydrochloride | α-Vitamin E | Nitazoxanide | Curcumin | N-Acetylneuraminic acid | Naringenin | Salcomine | Crystal Violet | β-Cyclodextrin |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Anti-Viral Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | Serotonin Receptor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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