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Postion:Product Catalog >API>Anesthetic Agents>Skeletal muscle relaxants>Chlorzoxazone
Chlorzoxazone
  • Chlorzoxazone
  • Chlorzoxazone
  • Chlorzoxazone
  • Chlorzoxazone
  • Chlorzoxazone

Chlorzoxazone NEW

Price Get Latest Price
Package ≥1kg ≥25kg ≥100kg
Min. Order: 1kg
Supply Ability: 20tons
Update Time: 2024-12-26

Product Details

Product Name: Chlorzoxazone CAS No.: 95-25-0
EC-No.: 202-403-9 Min. Order: 1kg
Purity: 99% Supply Ability: 20tons
Release date: 2024/12/26


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Product nameChlorzoxazone
CAS95-25-0
Appearancewhite powder
Assay99%
StorageCool and Protect from light


 
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Chlorzoxazone
Product Name Chlorzoxazone

CAS 95-25-0

MF C7H4ClNO2

MW 169.57

EINECS 202-403-9

MOL File 95-25-0.mol

Chemical Properties

Melting point 191-192 °C (lit.)
Density  1.3771 (rough estimate)
refractive index  1.5557 (estimate)
storage temp.  room temp
solubility  DMSO: soluble50mg/mL, clear
form  Powder
pka pKa 8.3 (Uncertain)
color  white to off-white
Water Solubility  0.1 g/100 mL
Merck  14,2194
CAS DataBase Reference 95-25-0(CAS DataBase Reference)
NIST Chemistry Reference Chlorzoxazone(95-25-0)
EPA Substance Registry System Chlorzoxazone (95-25-0)
 
 
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 Usage And Synthesis
Skeletal muscle relaxants

Chlorzoxazone is an orally active central skeletal muscle relaxant with its chemical structure being completely different with all the other muscle relaxants. It, mainly through acting on the central cerebral cortex and the spinal cord, inhibits the multi-synaptic reflection related to muscle spasms and produces muscle relaxation, further relieves the spasm caused pain and increase the flexibility of the muscles involved. Acetaminophen belongs to non-steroidal anti-inflammatory drugs and may mainly exert the analgesic and antipyretic effects through the inhibition of prostaglandin synthesis. Muscle relaxation studies through mouse traction test have demonstrated that the compound Chlorzoxazone showed a dose-dependent muscle relaxant effect with excellent protective effect on the strychnine-induced seizures in mice. The existence of paracetamol in the compound chlorzoxazone tablets can further enhance the effect of chlorzoxazone. Hot plate analgesic tests have showed the compound chlorzoxazone has a significant analgesic effect in a dose-dependent manner. It also has antagonism effect on the painful writhing of mice caused by antimony potassium tartratie in a good dose-response relationship. Test results have showed that acetaminophen and chlorzoxazone analgesic synergy.

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Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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