Chloropyramine NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Chloropyramine | CAS No.: 59-32-5 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Chloropyramine |
| Description | Chloropyramine is a competitive reversible H1 receptor antagonist that can be used in allergic conditions research, for example, conjunctivitis and bronchial asthma. Chloropyramine also shows anti-tumour activity in breast cancer [1] [2]. |
| In vitro | Chloropyramine at concentrations of 25 and 50 μM over periods of 24 and 48 hours has been shown to increase SASH1 expression and induce apoptosis in various breast cancer cell lines (T47D, MDA-MB-231, and BT-54). According to Western Blot analysis, enhanced SASH1 expression was observed after 24 hours at the given concentrations. Additionally, apoptosis was prominently induced after 48 hours of exposure to 50 μM Chloropyramine, as evidenced by apoptosis analysis. |
| In vivo | Chloropyramine (i.p.; 10 mg/kg) effectively counteracts histamine-induced hypothermia in rats. Utilizing an animal model comprising rats [2], the study administered a dosage of 10 mg/kg through the intraperitoneal route. The outcome highlighted a significant reduction in hypothermia triggered by histamine. |
| Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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