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Postion:Product Catalog >CGP-20712
CGP-20712
  • CGP-20712

CGP-20712 NEW

Price $350 $828 $1130
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: CGP-20712 CAS No.: 137888-49-4
Purity: 99.40% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCGP-20712
DescriptionCGP-20712 is a selective β 1-adrenoceptor antagonist with an IC50 of 0.7 nM.
In vitroIn brown adipocytes, CGP-20712 (1 μM) significantly inhibited UCP1 gene expression induced by NE. However, CGP-20712 had no effect on lipolysis. These results suggested that β1-adrenoceptor mediated UCP1 gene expression.[4] In neocortical membranes, CGP 20712 exhibited affinity for β1-adrenoceptor and β2-adrenoceptor with IC50 values of 0.7 and 6700 nM, respectively.[1]
In vivoCGP 20712 (a selective beta 1-adrenergic receptor antagonist) (5 mg/kg; Pretreatment of 8-day-old rats) did not change the plasma ACTH response to insulin injection.[3]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 45 mg/mL (91.01 mM)
KeywordsCGP-20712 | CGP20712
Inhibitors RelatedOlanzapine | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Phenylephrine hydrochloride | Isoprenaline hydrochloride | Amitriptyline hydrochloride | Labetalol hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride
Related Compound LibrariesBioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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