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Postion:Product Catalog >Cetrorelix Acetate
Cetrorelix Acetate
  • Cetrorelix Acetate

Cetrorelix Acetate NEW

Price $40 $77 $123
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Cetrorelix Acetate CAS No.: 145672-81-7
Purity: 97.96% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCetrorelix Acetate
DescriptionCetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.
In vitroGnRH-I antagonist Cetrorelix inhibited growth of ES-2 cell line only at 1000 ng/ml.?The incubation of ES-2 ovarian cancer cells in vitro with an GnRH-I antibody inhibited cell proliferation in a time and concentration-dependent manner.?GnRH-I may function as an autocrine growth factor in this ovarian cancer cell line [1].
In vivoCetrorelix inhibits the activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells by the GnRHR agonist [D-Trp6]GnRH (IC50 = 1.2 nM). In vivo, cetrorelix (60 μg per day) reduces tumor volume to 35% of control and decreases serum luteinizing hormone levels by 50% in a human epithelial ovarian cancer mouse xenograft model[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (33.53 mM)
KeywordsSB-75 | GnRH Receptor | Cetrorelix Acetate | Inhibitor | SB 75 | Gonadotropin releasing hormone receptor | inhibit | SB75 | GNRHR
Inhibitors RelatedHistrelin acetate | Nafarelin acetate(76932-56-4 free base) | Relugolix | Deslorelin acetate(57773-65-6 free base) | Ganirelix Acetate | Opigolix | Linzagolix choline | LGnRH-III, lamprey acetate(147859-97-0 free base) | Alarelin Acetate | Cetrorelix diacetate | Lecirelin acetate(61012-19-9 free base) | AG 045572
Related Compound LibrariesApproved Drug Library | Anti-Cancer Clinical Compound Library | Peptide Compound Library | Drug Repurposing Compound Library | NO PAINS Compound Library | Anti-Cancer Approved Drug Library | Clinical Compound Library | Anti-Cancer Compound Library | Human Metabolite Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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