Product Details
| Product Name:
Ceruletide |
CAS No.:
17650-98-5 |
| Purity:
98.47% |
Supply Ability:
10g |
| Release date:
2024/11/17 |
Product Introduction
Bioactivity
| 名稱 | Ceruletide |
| 描述 | Ceruletide is a decapeptide that is a safe and effective cholecystokinin and cholecystokinin receptor agonist with direct spasmodic effects on the gallbladder muscle and bile duct.[1] |
| 體外活性 | Ceruletide is biologically and chemically identical to the human gastrointestinal hormones cholecystokinin-pancreatin (CCK) and gastrin II；Ceruletide stimulates gallbladder contraction while delaying gastric emptying and inhibiting motility of the proximal duodenum [1]. Ceruletide activates NF-κB/Rel in vitro at high doses (but not physiological doses), which may induce a self-defense gene program before cell damage occurs and may protect pancreatic acinar cells from further damage after secretagogue overstimulation [2]. |
| 體內(nèi)活性 | Ceruletide (5-15 ng/kg intravenously) has a significant spasmodic effect on the pylorus in rats[1]; Ceruletide (0.4-0.5 mcg/kg intravenously; 3-4 mcg/kg subcutaneously) causes vomiting and defecation in conscious dogs [3]. |
| 存儲(chǔ)條件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 96 mg/mL (70.98 mM)
H2O : 100 mg/mL (73.94 mM)
|
| 關(guān)鍵字 | inhibit | Cholecystokinin Receptor | Inhibitor | FI 6934 | CCK Receptor | Ceruletide | FI6934 |
| 相關(guān)產(chǎn)品 | PHA-767491 | GV-150013X | Itriglumide | GV150013 | XL413 hydrochloride | Lintitript | N-Cbz-DL-tryptophan | Spiroglumide |
| 相關(guān)庫(kù) | 抗癌天然產(chǎn)物庫(kù) | 經(jīng)典已知活性庫(kù) | 抗癌上市藥物庫(kù) | FDA 上市藥物庫(kù) | 高通量篩選天然產(chǎn)物庫(kù) | 已知活性化合物庫(kù) | GPCR靶點(diǎn)分子庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$0.00/25KG |
VIP5Y
|
Hebei Mojin Biotechnology Co., Ltd
|
2023-09-28 |
|
|
$500.00/10mg |
VIP6Y
|
Cellmano Biotech Limited
|
2019-09-20 |
|
|
$8.80/1KG |
VIP7Y
|
Career Henan Chemical Co
|
2019-07-04 |
United States