Cerulenin NEW
| Price | $94 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Cerulenin | CAS No.: 17397-89-6 |
| Purity: 98% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Cerulenin |
| 描述 | Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus. |
| 體外活性 | Cerulenin had a similar effect as StAR overexpression.StAR attenuated lipid synthesis and uptake as well as PA-induced inflammation and reduction in NO bioavailability in aortic endothelial cells. StAR can ameliorate endothelial dysfunction induced by PA via reducing the intracellular lipid levels[1]. |
| 體內(nèi)活性 | The histological profile of ob/ob livers that received cerulenin treatment demonstrated a dramatic reduction in lipid content, which was dose and time dependent. Seven-day treatment of 60 mg/kg cerulenin daily or every other day demonstrated the greatest decrease of fat staining and in some areas of the liver, ORO staining was absent ( Fig. 3D–F ). Two-day treatment of 60 mg/kg cerulenin resulted in a modest reduction in fat content. In contrast, cerulenin given 30 mg/kg was less effective than 60 mg/kg doses, but its effect on fat content was still obvious except for 2-day treatment (data not shown)[2]. |
| 存儲條件 | store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : Soluble DMSO : 90 mg/mL (403.10 mM), Sonication is recommended. |
| 關(guān)鍵字 | Inhibitor | Antibiotic | Fatty Acid Synthase (FASN) | Cerulenin | Fungal | inhibit |
| 相關(guān)產(chǎn)品 | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Geraniol | EDTA copper(II) disodium salt |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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