Ceramides Mixture NEW
| Price | $32 | $45 | $74 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Ceramides Mixture | CAS No.: 100403-19-8 |
| Purity: mixture | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Ceramides Mixture |
| Description | Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activity. |
| In vitro | Endogenous Ceramides inhibits mRNA synthesis of telomerase reverse transcriptase and telomerase activity via inactivation of the c-Myc transcription factor in the A549 human lung adenocarcinoma cell line. The sustained generation of long-chain endogenous ceramide requires the biochemical recycling of the sphingosine backbone of C6-ceramide, which involves deacylation and reacylation of ceramide for the generation of endogenous long-chain ceramide, most likely by CoA-dependent ceramide synthase, which is inhibited by fumonisin B1. In A549 cells the generation of long-chain endogenous ceramide mediates the effects of exogenous C6-ceramide on growth inhibition, cell cycle arrest, and the modulation of telomerase activity [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Methanol : < 1 mg/mL (insoluble or slightly soluble) Ethanol : 1 mg/ml, Sonication and heating for 30 minutes are recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : < 1 mg/mL (insoluble or slightly soluble) Chloroform : 7.69 mg/ml |
| Keywords | inhibit | permeability | transcription | CoA | Golgi | Inhibitor | Telomerase | Ceramides Mixture | mRNA | c-Myc | lipid | cell-cycle | barrier | Endogenous |
| Inhibitors Related | Cyclogalegenin | TMPyP4 tosylate | BIBR 1532 | Zidovudine | Braco-19 trihydrochloride | Costunolide | RHPS4 | L-778123 hydrochloride | MST-312 | Adefovir |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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